Biology: A new type of cell with regenerative capacity in human lungs
It was discovered by the University of Pennsylvania a new type of cell in the lungs human, which is capable of performing a key role in lung disease. The researchers analyzed human lung tissue to find new cells, called respiratory airway secretory cells. These cells line tiny branches of the airways near the alveolar structures where oxygen is exchanged for carbon dioxide.
These cells have stem cell-like properties that allow them to regenerate further cells essential for the regular functioning of the alveoli. They also found evidence that cigarette smoking and COPD chronic obstructive pulmonary disease, they can interrupt this regeneration process of these cells. This suggests that correcting this disruption could be a good way to treat this condition.
Biology, a new cell type with regenerative capabilities found
COPD is a devastating and common disease, but we don’t really understand the cellular biology of why or how some patients develop it. Identifying new cell types, particularly new progenitor cells, that are damaged in COPD could indeed accelerate the development of new treatments. It typically has progressive damage and loss of alveoli, exacerbated by chronic inflammation. It is estimated to affect around 10% of people e cause approximately 3 million deaths each year worldwide. ******* medications are prescribed, but these treatments can only slow down the disease process rather than stop or reverse it.
The new study uncovered evidence of these cells while examining gene activity signatures of lung cells sampled from healthy human donors. They soon recognized that the RASC, which do not exist in the lungs of the mouse, are secretory cells that reside near the alveoli and produce the proteins necessary for the fluid lining of the airways. Observations of the similarities in gene activity between RASC and an important progenitor cell in the alveoli called AT2 cells led the team to a further discovery: RASCs, in addition to their secretory function, serve as predecessors for AT2 cells, regenerating them to maintain the AT2 population and keep alveoli healthy.
AT2 cells become abnormal in COPD and other lung diseases, and the researchers found evidence that i defects in the RASCs could be an upstream cause of these anomalies. In the lung tissue of people with COPD, as well as people without COPD who have a history of smoking, they observed many AT2 cells that were altered in a way that suggested defective transformation from RASC to AT2. More research is needed at the moment, but the findings suggest the possibility of future treatments for this conditionrestoring the normal differentiation process from RASC to AT2 or even replenishing the normal RASC population in the damaged lungs.
Image by Ernesto Eslava from Pixabay
- android | how to open all the applications of your mobile in split… The Android split screen It is a function that was created for the first time at the beginning of the…
- Android: what are the best keyboard applications for your cell phone |… One of the most outstanding features that smartphones brought was the default touch keyboard that characterizes each cell phone brand;…
- The T cell may be able to kill all types of cancer A recently discovered cell in ours immune system it could be the focus of important research and it could treat…
- What is the Android cell phone key hole for? – The Sun of Toluca Smartphones with the Android operating system introduce new features from time to time, ranging from software configurations to accessories to…
- So you can have the appearance of the iPhone on an Android cell phone One of the strong points of the iPhone is in the aesthetics of the software and therefore, it is not…
- android | why it is not recommended to leave applications open in the… All mobile phones with Android operating system They have three digital buttons at the bottom: first, the “back” button, which…
- Google Assistant: tutorial to delete your history on an Android mobile… Lima, 05/15/2022 05:52 am Cell phones with Android operating system have a virtual assistant to which various queries can be…
- How to download WhatsApp Aero 2022 on an Android cell phone Mexico City.- Every day technology advances by leaps and bounds and applications innovate to offer their best versions to users.…
- android | which is the most used emoticon in each country |… Every time users communicate through an instant messaging application, be it WhatsApp, Telegram, Messenger, etc., it is customary to use…
- android | how to create a short film with my videos from the image… All smartphones with Android OS, regardless of their brand or model, have an image gallery, a place where users store…
- Cell death allows us to discover the origins of life A team of scientists from the University of Bristol has found that organelles continue to live after cell death, overturning…
- WhatsApp will stop working from April 30 on these cell phones WhatsApp will stop working on a long list of phones from April 30, 2022, after the service changed its privacy…
- android | how to color an old photograph that is in black and white |… Nowadays, it is likely that more than one person has digitized the photographs of their family albums, however, if some…
- android | The trick so that the deleted photos and videos do not go to… One of the worst situations in which you can find yourself is that your Android mobile phone no longer has…
- Instead of a new Splinter Cell game, Ubisoft forces Sam Fisher to do a… Why does Ubisoft like to play with our emotions so much? First, it adds the Prince of Persia to For…
- The new Samsung T5s continue a saga of excellent external SSD drives The new ones Samsung T5 with small units, with a SATA M.2 drive inside, that can be connected to both…
- android | the trick so that you have the three physical buttons of the… There is no smartphone with Android operating system that does not have the following physical buttons: volume up or down,…
- Android: how to have free Wi-Fi on your cell phone without a password… Have you ever run out of signal or data and have not been able to finish what you were doing…
- Cell Phones | Tricks | android | iOS | Do you want to improve your… Searching for an unknown word in Google It has become an essential action in our lives, especially when said word…
- Facebook | Cell Phones | Why do you prefer Samsung? Mark Zuckerberg’s… Mark Zuckerberg, the co-founder of Facebook, revealed that he prefers to use a Samsung cell phone in an interview with…
- WhatsApp: how to send audios with Auronplay’s voice and without… AuronPlay, one of the world’s most popular streamers, is making waves on social media as thousands of fans are trying…
- iOS | how to hide your personal photos and videos from iPhone gallery… All Apple mobile devices, we are talking about iPhones, automatically store any photo or video that you capture with the…
- E3 2016: Resident Evil 7 Producer Destroyed Over Silent Hills… Resident Evil 7 seems to have taken some inspiration from PT, the Silent Hills demo. However, according to producer Masachika…
- android | see what happens to your phone if you charge it from the USB… When your Android cell phone is a few minutes away from turning off due to the little energy it has…
- Smartphone: how to write in a Word document using your voice and… In general, most people who write documents in Microsoft Word It usually takes a long time, especially if they are…
- iOS: list of iPhone cell phones compatible with wireless charging |… Some high-end models with the iOS operating system incorporate wireless charging, that is, the battery can be powered without the…
- Cell Phones | android | iOS | How To Schedule Fake Calls To Escape… One thing you never thought your smartphone could help you with is getting rid of embarrassing situations, places you don’t…
- Android: the 4 reasons why it is convenient to turn off the cell phone… One of the main problems that arise when we take the cell phone to be fixed or when we want…
- iOS | how to reset an iPhone without losing your data | Restore |… There are many factors for you to decide to factory reset your mobile with the iOS operating system, for example,…
- E3 2019: A New Splinter Cell Game Isn’t In Development, Kotaku Sources… We all want it, right? A new Splinter Cell game has been at the top of our wish lists for…
- Mass Effect: Andromeda Beta Cancellation Explained, BioWare Apologizes In case you missed any previous news, BioWare has canceled the Mass Effect: Andromeda Multiplayer Beta. Potential participants signed up…
- So you can make your cell phone emit a sound when it reaches 100%… Night is coming, you’re getting ready for the party and you want to make sure your phone is charging properly…
- android | How to improve the speed of your cell phone | Applications |… Many people have in their hands a cell phone with a variety of ranges; However, sometimes our mobile device tends…
- In hours the app will stop working on these cell phones There is less and less to say “goodbye” WhatsApp” to various cell models. The Meta-owned instant messaging platform announced a…
- What is the little hole that cell phones have on one edge for? Android devices are used in many parts of the world, but very few know the usefulness of a small hole…
- How to root an Android phone: what it is and why so many permissions… Benefits 1. Allows you to customize mobile in different ways 2. Add android modified versions 3. Uninstall applications that, either…
- Parkinson’s, stem cell tests give positive results: the cure is closer The results are promising and represent the last step before the clinical trial in humans, which should start by the…
- Radiation and cell phones: Apple and Samsung have been called to court Apple And Samsung have been cited in a lawsuit because of some testimonials according to which their mobile phones would…
- android | how to configure Voice Match so that your cell phone… Voice Match is a tool that can be found within the settings of the main Google application, it basically serves…
- 4 tricks on your cell phone that will surprise you – PressPerú Lima.- Know all the benefits of your cell phone. Many times you may think that you know all its functions,…
- How to activate the hidden camera on Android cell phone Now it is possible to get the most out of your mobile with the hidden camera that phones with Android…
- android | Why you should activate “airplane mode” during a flight |… Android phones have a series of improvements in both processor and battery. However, there are details that do not escape…
- Did you know that you have an SOS button on your cell phone? so you… For Juan Lucas Bello A smartphone today is almost an extension of the body, so it must be prepared for…
- Monster Hunter: World Training Area looks like an excellent addition… Subscribe to Maxi Game on Continuing their coverage of Monster Hunter: World, Game Informer has released a new video detailing…
- android | how to enable dual camera on my samsung phone | Applications… Samsung’s “S” line mobile devices have surprised their millions of users with one of the most innovative tools, which they…
- android | how to discover all the users that are connected to my WiFi… Currently there are two types of connections to access the Internet: the first, through the cables that go directly from…
- Android: the trick to scan a QR code from a photo or screenshot | Cell… QR codes have become increasingly popular. They work to add contacts, connect to a Wi-Fi network or make payments. Many…
- Do you have Android and use it for work? 4 applications that cannot be… For many people, the mobile phone has become an important tool when it comes to working, especially if they continue…
- With these 4 codes you can know if your cell phone has been spied on –… By Juan Lucas Bello The Android operating system is customizable and easy to use for programmers and developers, for this…
- android | how to organize my cell phone contacts in different folders… Every time you are introduced to a person, they will probably ask for their mobile number so that you are…